Programmable specificity.
Guide RNA sequences direct the editing system toward conserved viral elements while preserving healthy host DNA.
The Excision platform
A precise cut at the source of persistence.
Viruses evolve. Patients adapt. Our science is focused on the hidden biology that keeps chronic infection in place.
The problem
Suppression is not the same as a cure.
Current antiviral therapies can be life-changing, but for many infections they require daily or periodic treatment for life. When therapy stops, the viral reservoir can reactivate.
THE HIDDEN RESERVOIR
Viral DNA can persist inside the cell.
That is the biological space we are designed to reach: the integrated or episomal viral DNA that conventional medicines cannot remove.
How it worksFrom target recognition
From target recognition
to lasting impact.
Our approach pairs programmable nucleases with delivery and molecular design strategies engineered for viral targets.
Excise the reservoir.
Precisely designed cuts are intended to disrupt or remove viral genetic material that enables persistence.
Make it therapeutic.
We build for the realities of patients: delivery, tolerability, repeatability and a clear path to the clinic.
Our research lens
Rigorous science.
Human scale.
Every experiment starts with the same question: can this meaningfully change the lives of people who have spent years managing their disease?
01 / DESIGN
Built for selectivity.
We interrogate target biology, off-target risk and delivery constraints together—not as disconnected steps.
02 / VALIDATE
Evidence before excitement.
Our translational decisions are anchored in reproducible data and a disciplined understanding of what it takes to move forward.
03 / LISTEN
Patient needs in the room.
The best endpoint is not just a molecular one. It is a patient who can plan a future beyond chronic management.
A platform in motion
The science is becoming a pipeline.
Explore the programs taking our platform from concept to the next stage of development.
Explore programs ↗